3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole

Base Information

• Chemical Name: 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole
• CAS No.: 170959-52-1
• Molecular Formula: C₁₃H₁₂N₄OS
• Molecular Weight: 272.33
• Mol file: 170959-52-1.mol

Synonyms:3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole

Chemical Property of 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole

There total 5 articles about 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-(5-methyl-4-oxazoyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (170959-35-0) + methyl iodide (74-88-4) → 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole (170959-52-1)

Guidance literature:

With sodium hydroxide; In ethanol;

DOI:10.1002/jhet.5570320424

Reference yield:

phenyl isothiocyanate (103-72-0) → 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole (170959-52-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / 2n aq. NaOH / ethanol / 24 h / Ambient temperature

2: 89 percent / 5percent aq. Na₂CO₃ / 4 h / Heating

3: 95 percent / NaOH / ethanol

With sodium hydroxide; sodium carbonate; In ethanol;

DOI:10.1002/jhet.5570320424

Reference yield:

5-methyloxazole-4-carboxylic acid hydrazide (170959-36-1) → 3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole (170959-52-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / 2n aq. NaOH / ethanol / 24 h / Ambient temperature

2: 89 percent / 5percent aq. Na₂CO₃ / 4 h / Heating

3: 95 percent / NaOH / ethanol

With sodium hydroxide; sodium carbonate; In ethanol;

DOI:10.1002/jhet.5570320424

upstream raw materials:

5-(5-methyl-4-oxazoyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

methyl iodide

phenyl isothiocyanate

5-methyloxazole-4-carboxylic acid hydrazide