5-Methyl-1,3-oxazole-4-carbohydrazide

Base Information

• Chemical Name: 5-Methyl-1,3-oxazole-4-carbohydrazide
• CAS No.: 170959-36-1
• Molecular Formula: C5H7N3O2
• Molecular Weight: 141.13
• European Community (EC) Number: 874-804-2
• Mol file: 170959-36-1.mol

Synonyms:5-methyl-1,3-oxazole-4-carbohydrazide;170959-36-1;5-Methyloxazole-4-carbohydrazide;4-Oxazolecarboxylicacid,5-methyl-,hydrazide(9CI);MFCD18447663;AKOS005138147;BS-37440;CS-0246702;EN300-3402286

Chemical Property of 5-Methyl-1,3-oxazole-4-carbohydrazide

Chemical Property:

• PKA: 10.96±0.10(Predicted)
• PSA: 81.15000
• Density: 1.291±0.06 g/cm3(Predicted)
• LogP: 0.67770
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 141.053826475
• Heavy Atom Count: 10
• Complexity: 139

Purity/Quality:

99% ^*data from raw suppliers

5-methyl-1,3-oxazole-4-carbohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(N=CO1)C(=O)NN

Technology Process of 5-Methyl-1,3-oxazole-4-carbohydrazide

There total 1 articles about 5-Methyl-1,3-oxazole-4-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5-Methyloxazol-4-carbonsaeure-methylester (41172-57-0) → 5-methyloxazole-4-carboxylic acid hydrazide (170959-36-1)

Guidance literature:

With hydrazine; In methanol; for 0.0833333h;

DOI:10.1002/jhet.5570320424

Reference yield: 85.0%

phenyl isothiocyanate (103-72-0) + 5-methyloxazole-4-carboxylic acid hydrazide (170959-36-1) → 1-(5-methyloxazole-4-carboxyl)-4-phenylthiosemicarbazide (170959-44-1)

Guidance literature:

With sodium hydroxide; In ethanol; for 24h; Ambient temperature;

DOI:10.1002/jhet.5570320424

Reference yield: 72.0%

5-methyloxazole-4-carboxylic acid hydrazide (170959-36-1) + isothiocyanatocyclohexane (1122-82-3) → 4-cyclohexyl-1-(5-methyloxazole-4-carboxyl)thosemicarbazide

Guidance literature:

With sodium hydroxide; In ethanol; for 24h; Ambient temperature;

DOI:10.1002/jhet.5570320424

upstream raw materials:

5-Methyloxazol-4-carbonsaeure-methylester

Downstream raw materials:

1-(5-methyloxazole-4-carboxyl)-4-phenylthiosemicarbazide

5-(5-methyl-4-oxazoyl)-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

3-(4-methyl-4-oxazoyl)-4-phenyl-5-methylthio-4H-1,2,4-triazole