trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester

Base Information

• Chemical Name: trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester
• CAS No.: 478837-20-6
• Molecular Formula: C₉H₈F₃NO₅S
• Molecular Weight: 299.227
• Mol file: 478837-20-6.mol

Synonyms:trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester

Chemical Property of trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester

There total 1 articles about trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trifluoromethylsulfonic anhydride (358-23-6) + 2,3-dimethyl-4-nitrophenol (19499-93-5) → trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester (478837-20-6)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 90.9%

potassium cyanide + trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester (478837-20-6) → 2,3-dimethyl-4-nitrobenzonitrile (52962-97-7)

Guidance literature:

With tetrakistriphenylphosphine; In tetrahydrofuran; for 10h; Heating / reflux;

Reference yield: 6.8%

trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester (478837-20-6) + nortropine (538-09-0) → endo-8-(2,3-dimethyl-4-nitro-phenyl)-8-azabicyclo[3.2.1]octan-3-ol

Guidance literature:

With pyridine; at 110 ℃; for 16h;

upstream raw materials:

trifluoromethylsulfonic anhydride

2,3-dimethyl-4-nitrophenol

Downstream raw materials:

4-methyl-1H-indazole-5-carbonitrile

2,3-dimethyl-4-nitrobenzonitrile