19499-93-5

Usage

Uses

Used in Organic Synthesis:
2,3-DIMETHYL-4-NITROPHENOL is used as an intermediate for the synthesis of a variety of organic compounds, contributing to the development of new chemical entities and materials.
Used in Chemical Reactions:
As a reagent, 2,3-DIMETHYL-4-NITROPHENOL is employed in various chemical reactions, facilitating the synthesis of pharmaceuticals and agrochemicals, which are essential for medical and agricultural applications.
Used in Pharmaceutical Industry:
2,3-DIMETHYL-4-NITROPHENOL is used as a precursor in the production of pharmaceuticals, playing a crucial role in the development of new drugs and improving existing ones.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 2,3-DIMETHYL-4-NITROPHENOL is utilized as a precursor for the synthesis of agrochemicals, which are vital for crop protection and enhancement of agricultural productivity.
Given the compound's potential hazards, it is imperative that 2,3-DIMETHYL-4-NITROPHENOL is handled with care, using appropriate safety measures to mitigate risks associated with its use in these applications.

InChI:InChI=1/C8H9NO3/c1-5-6(2)8(10)4-3-7(5)9(11)12/h3-4,10H,1-2H3

Upstream product

• 81029-03-0 4-Methoxy-2,3-dimethylnitrobenzene 
• 526-75-0 2,3-Dimethylphenol 
• 74783-54-3 1-hydroxy-2,3-dimethyl-4-nitrosobenzene 
• 2944-49-2 2,3-dimethylanisole 
• 19499-92-4 carbonic acid bis-(2,3-dimethyl-phenyl ester) 

Downstream Products

• 19499-94-6 1-(benzyloxy)-2,3-dimethyl-4-nitrobenzene 
• 478837-20-6 trifluoromethanesulfonic acid 2,3-dimethyl-4-nitrophenyl ester 
• 3096-69-3 4-amino-2,3-dimethylphenol 
• 52962-97-7 2,3-dimethyl-4-nitrobenzonitrile 
• 478837-29-5 4-methyl-1H-indazole-5-carbonitrile 
• 478837-27-3 N-(4-cyano-2,3-dimethylphenyl)acetamide 
• 478837-24-0 4-amino-2,3-dimethylbenzonitrile 
• 1207868-95-8 C₂₂H₁₇NO₃ 
• 1207869-67-7 (5-(benzyloxy)-4-methyl-1H-indol-2-yl)(4-phenoxyphenyl)methanone 
• 1207869-65-5 5-(benzyloxy)-4-methyl-1H-indole-2-carbaldehyde 
• 1207869-63-3 ethyl 3-(3-(benzyloxy)-2-methyl-6-nitrophenyl)-2-oxopropanoate 
• 1207869-66-6 C₂₉H₂₅NO₃ 
• 19499-95-7 5-benzyloxy-4-methyl-indole-2-carboxylic acid 
• 286371-45-7 4-[(6,7-dimethoxy-4-quinolyl)oxy]-2,3-dimethylaniline 

Relevant academic research and scientific papers

PROCESS FOR PREPARING 1, 2-BENZENEDIMETHANOL COMPOUND

A process for preparing a compound represented by Formula [1], the process comprising a step of hydrolyzing a compound represented by Formula [2] under an acidic or basic condition, and a step of reacting a compound represented by Formula [3] with a metal acetate salt, and a step of halogenating a compound represented by Formula [4]; a process for preparing a compound represented by Formula [1] comprising a step of reacting a compound represented by Formula [3] with a metal acetate salt, and then, adding alcohol, water, or base to the reaction solution to perform reaction; a process for preparing a compound represented by Formula [1] comprising a step of reacting a compound represented by Formula [3] under a presence or absence of a base, an ionic liquid and a metal sulfate salt, in water or a mixed solvent of water and an organic solvent; a compound represented by Formula [2] or a salt of the same; and a compound represented by Formula [3] or a salt of the same.

FORMATION OF DIENONES ON THE REACTION OF CRESOLS, XYLENOLS, AND 2-NAPHTHOL WITH NITROGEN DIOXIDE: OBSERVATION OF KETO TAUTOMERS OF NITROPHENOLS

Reaction of o- and p-cresol, the xylenols, and 2-naphthol with nitrogen dioxide gives nitrocyclohexadienones and nitrophenols.Secondary nitrodienones, the keto tautomers of the nitrophenols, have been observed in several cases and are intermediates in the formation of the nitrophenols.

ipso Nitration. XXIV. Nitration of 2-methylphenols. Formation and rearrangement of 6-methyl-6-nitrocyclohexa-2,4-dienones

Nitration of o-cresol and some mono-, di-, and trimethyl derivatives in acetic anhydride at -60 deg C gives 6-methyl-6-nitrocyclohexa-2,4-dienones.The dienones are more labile than the isomeric 4-methyl-4-nitrocyclohexa-2,5-dienones and, if the 2-position of the dienone is not blocked, undergo regiospecific rearrangement to 6-nitro-o-cresols. 2,3,6-Trimethyl- and 2,3,5,6-tetramethylphenol also give a 2,5-dienone with nitro attached to a secondary carbon.