Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1R,2S)-rel- (9CI)

Base Information

• Chemical Name: Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1R,2S)-rel- (9CI)
• CAS No.: 111955-06-7
• Molecular Formula: C₉H₁₃ClO₃
• Molecular Weight: 204.653
• Mol file: 111955-06-7.mol

Synonyms:Cyclohexanecarboxylicacid, 2-(chlorocarbonyl)-, methyl ester, cis-(?à)-; Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-,methyl ester, cis-

Chemical Property of Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1R,2S)-rel- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1R,2S)-rel- (9CI)

There total 2 articles about Cyclohexanecarboxylic acid, 2-(chlorocarbonyl)-, methyl ester, (1R,2S)-rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S*,2S*)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid (2484-60-8,2778-62-3,7719-08-6,52782-07-7,88335-91-5,88335-92-6,96894-64-3,111955-05-6) → (+/-)-trans-2-chlorocarbonyl-cyclohexanecarboxylic acid methyl ester (52479-89-7,52841-95-9,71606-03-6,111955-06-7,147201-81-8)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; for 2h;

Reference yield:

oxalyl dichloride (79-37-8) → (+/-)-trans-2-chlorocarbonyl-cyclohexanecarboxylic acid methyl ester (52479-89-7,52841-95-9,71606-03-6,111955-06-7,147201-81-8)

Guidance literature:

With benzene;

Reference yield:

(+/-)-trans-2-chlorocarbonyl-cyclohexanecarboxylic acid methyl ester (52479-89-7,52841-95-9,71606-03-6,111955-06-7,147201-81-8) + diazomethyl-trimethyl-silane (18107-18-1) → rac-methyl 2-(2-chloroacetyl)cyclohexanecarboxylate

Guidance literature:

(+/-)-trans-2-chlorocarbonyl-cyclohexanecarboxylic acid methyl ester; diazomethyl-trimethyl-silane; In 1,4-dioxane; at 20 ℃; for 1h;

With hydrogenchloride; In 1,4-dioxane; diethyl ether; water;

upstream raw materials:

oxalyl dichloride

(1S*,2S*)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid

Downstream raw materials:

(+/-)-trans-2-phenylcarbamoyl-cyclohexanecarboxylic acid methyl ester