Technology Process of 1-benzoyl-1'-N,N-dimethylferrocenecarboxamide
There total 1 articles about 1-benzoyl-1'-N,N-dimethylferrocenecarboxamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
AlCl3;
In
dichloromethane;
C6H5COCl in CH2Cl2 was added dropwise to a suspn. of AlCl3 in CH2Cl2 at -30°C, a soln. of complex in CH2Cl2 was added dropwise during 10 min, the mixt. was stirred at -30°C for 1 h, at 0°C for 5 h; poured into ice-water, extd. with CH2Cl2, washed with satd. Na2CO3 and water, dried over MgSO4, flash column chromy. (silica gel, acetone-hexanes); as oil;
DOI:10.1039/b313422a
- Guidance literature:
-
With
AlCl3; LiAlH4;
In
diethyl ether;
a soln. of AlCl3 in ether was added dropwise to a suspn. of LiAlH4 in ether, a soln. of complex in ether was added dropwise, the mixt. was refluxed for 2 h; H2O was added, 2 M NaOH, the water layer was extd. with ether, dired with MgSO4, concd., flahs column chromd. (silica gel, acetone-hexanes with 1% Et3N); an oil was solidified under high vac., crystd. from hexanes for 3 weeks at 0°C; elem. anal.;
DOI:10.1039/b313422a
