N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine

Base Information

Chemical Name:N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine
CAS No.:111697-11-1
Molecular Formula:C₁₃H₂₂ClN₃
Molecular Weight:255.791
Hs Code.:
DSSTox Substance ID:DTXSID00549500
Wikidata:Q82428562
Mol file:111697-11-1.mol

Synonyms:111697-11-1;N,N-DIBUTYL-4-CHLORO-6-METHYLPYRIMIDIN-2-AMINE;2-DIBUTYLAMINO-4-CHLORO-6-METHYLPYRIMIDINE;DTXSID00549500

Suppliers and Price of N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine

Chemical Property:

Boiling Point:92-93 °C(Press: 0.01 Torr)
PKA:4?+-.0.10(Predicted)
PSA：29.02000
Density:1.060±0.06 g/cm3(Predicted)
LogP:3.84500
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:255.1502254
Heavy Atom Count:17
Complexity:193

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCN(CCCC)C1=NC(=CC(=N1)Cl)C

Technology Process of N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine

There total 4 articles about N,N-Dibutyl-4-chloro-6-methylpyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 55447-64-8
2-N,N-dibutylamino-6-methylpyrimidin-4-ol

: 111697-11-1
4-chloro-2-N,N-di-n-butylamino-6-methylpyrimidine

Guidance literature:: With trichlorophosphate; for 3h; Heating;
DOI:10.1002/jhet.5570240137

Reference yield:

: 22536-64-7
2-chloro-4-methoxy-6-methyl-pyrimidine

: 111697-11-1
4-chloro-2-N,N-di-n-butylamino-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / ethanol / 88 °C / overnight, stainless steel pressure vessel

2: 78 percent / 6 N hydrochloric acid / Heating; overnight

3: 89 percent / POCl₃ / 3 h / Heating

With hydrogenchloride; trichlorophosphate; In ethanol;
DOI:10.1002/jhet.5570240137

Reference yield:

: 111-92-2
dibutylamine

: 111697-11-1
4-chloro-2-N,N-di-n-butylamino-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / ethanol / 88 °C / overnight, stainless steel pressure vessel

2: 78 percent / 6 N hydrochloric acid / Heating; overnight

3: 89 percent / POCl₃ / 3 h / Heating

With hydrogenchloride; trichlorophosphate; In ethanol;
DOI:10.1002/jhet.5570240137