tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

Base Information

Chemical Name:tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate
CAS No.:847956-79-0
Molecular Formula:C₂₄H₃₇N₃O₅
Molecular Weight:447.575
Hs Code.:

Synonyms:tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

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Chemical Property of tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

Chemical Property:

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Technology Process of tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

There total 1 articles about tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 847956-78-9
tert-butyl (1R,3S,4S)-4-amino-3-isopropylcyclohexylcarbamate

: 1138-80-3
N-(Benzyloxycarbonyl)glycine

: 847956-79-0
tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

Guidance literature:: With 4-methyl-morpholine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 12h;

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 847956-79-0
tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate

: 67-64-1
acetone

: 76-05-1
trifluoroacetic acid

: 847956-81-4
benzyl 2-((1S,2S,4R)-2-isopropyl-4-(isopropyl(methyl)amino)cyclohexylamino)-2-oxoethylcarbamate trifluoroacetate

Guidance literature:: tert-butyl (1R,3S,4S)-4-(2-benzyloxycarbonylaminoacetamido)-3-isopropylcyclohexylcarbamate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 0.5h;

acetone; With sodium tris(acetoxy)borohydride; In dichloromethane; for 1.5h;

formaldehyd; trifluoroacetic acid; With sodium tris(acetoxy)borohydride; more than 3 stages;