chloro(5-oxo-2,5-dihydrofuran-3-yl)methyl acetate

Base Information

• Chemical Name: chloro(5-oxo-2,5-dihydrofuran-3-yl)methyl acetate
• CAS No.: 125973-98-0
• Molecular Formula: C₇H₇ClO₄
• Molecular Weight: 190.583
• Mol file: 125973-98-0.mol

Synonyms:

Chemical Property of chloro(5-oxo-2,5-dihydrofuran-3-yl)methyl acetate

Chemical Property:

• Vapor Pressure: 0.000859mmHg at 25°C
• Boiling Point: 304.7°C at 760 mmHg
• Flash Point: 140.5°C
• Density: 1.416g/cm³

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of chloro(5-oxo-2,5-dihydrofuran-3-yl)methyl acetate

There total 2 articles about chloro(5-oxo-2,5-dihydrofuran-3-yl)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxymethyl-5H-furan-2-one (80904-75-2) → 4-(Acetoxychloromethyl)-2(5H)-furanone (125973-98-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / pyridinium chlorochromate, NaCl / CH₂Cl₂ / 1.7 h / Ambient temperature

2: AlCl₃ / 48 h / Ambient temperature

With aluminium trichloride; pyridinium chlorochromate; sodium chloride; In dichloromethane;

DOI:10.1021/jo00296a053

Reference yield:

4-formylfuran-1(5H)-one (125973-97-9) + acetyl chloride (75-36-5) → 4-(Acetoxychloromethyl)-2(5H)-furanone (125973-98-0)

Guidance literature:

With aluminium trichloride; for 48h; Ambient temperature;

DOI:10.1021/jo00296a053

upstream raw materials:

4-formylfuran-1(5H)-one

acetyl chloride

4-hydroxymethyl-5H-furan-2-one

Refernces