Technology Process of FAM-C6-TPP
There total 4 articles about FAM-C6-TPP which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(6-ammoniohexyl)triphenylphosphonium bromide trifluoroacetic acid; 6-carboxyfluorescein diacetate;
With
triethylamine;
In
N,N-dimethyl-formamide;
With
methanol;
In
N,N-dimethyl-formamide;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium bromide / acetonitrile; N,N-dimethyl-formamide / 48 h / Reflux
2.1: chlorotriisopropylsilane / dichloromethane / 2 h
3.1: triethylamine / N,N-dimethyl-formamide
3.2: 0.5 h
With
chlorotriisopropylsilane; triethylamine; potassium bromide;
In
dichloromethane; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine / dichloromethane / 0 °C
2.1: triethylamine / dichloromethane / 0 - 20 °C
3.1: potassium bromide / acetonitrile; N,N-dimethyl-formamide / 48 h / Reflux
4.1: chlorotriisopropylsilane / dichloromethane / 2 h
5.1: triethylamine / N,N-dimethyl-formamide
5.2: 0.5 h
With
chlorotriisopropylsilane; triethylamine; potassium bromide;
In
dichloromethane; N,N-dimethyl-formamide; acetonitrile;