4-(2,4-Difluorophenyl)butanoic acid

Base Information

Chemical Name:4-(2,4-Difluorophenyl)butanoic acid
CAS No.:110931-78-7
Molecular Formula:C10H10 F2 O2
Molecular Weight:200.185
Hs Code.:
Mol file:110931-78-7.mol

Synonyms:4-(2,4-DIFLUOROPHENYL)BUTANOIC ACID;110931-78-7;Benzenebutanoic acid,2,4-difluoro-;2,4-DIFLUOROPHENYLBUTYRIC ACID;SCHEMBL6956901;IFFOGNBDGRXWFK-UHFFFAOYSA-N;4-(2,4-difluorophenyl)butyric acid;MFCD06810482;CS-0441170;EN300-1846338

Suppliers and Price of 4-(2,4-Difluorophenyl)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(2,4-Difluorophenyl)butanoicacid 97%
1g
$ 371.00

Alichem
4-(2,4-Difluorophenyl)butanoicacid
5g
$ 1715.64

Alichem
4-(2,4-Difluorophenyl)butanoicacid
1g
$ 572.22

Acrotein
4-(2,4-Difluorophenyl)butanoicacid 97%
1g
$ 124.67

Total 9 raw suppliers

Chemical Property of 4-(2,4-Difluorophenyl)butanoic acid

Chemical Property:

Vapor Pressure:0.000973mmHg at 25°C
Refractive Index:1.5
Boiling Point:290.1°C at 760 mmHg
PKA:4.70±0.10(Predicted)
Flash Point:129.3°C
PSA：37.30000
Density:1.264g/cm³
LogP:2.37210
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:200.06488588
Heavy Atom Count:14
Complexity:197

Purity/Quality:

98%min ^*data from raw suppliers

4-(2,4-Difluorophenyl)butanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)F)CCCC(=O)O

Technology Process of 4-(2,4-Difluorophenyl)butanoic acid

There total 10 articles about 4-(2,4-Difluorophenyl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 405196-44-3
4-(2,4-difluorophenyl)butanoic acid 1,1-dimethylethyl ester

: 110931-78-7
4-(2,4-difluorophenyl)butanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1021/jo0160322

Reference yield:

: 110931-77-6
4-(2,4-difluorophenyl)-4-oxobutanoic acid

: 110931-78-7
4-(2,4-difluorophenyl)butanoic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; amalgamated zinc; hydrogen; acetic acid; palladium on activated charcoal; Yield given. Multistep reaction; 1.) toluene, reflux, 8 h, 2.) RT, 36 h;
DOI:10.1021/jm00071a011