2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide

Base Information

• Chemical Name: 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide
• CAS No.: 1346513-21-0
• Molecular Formula: C₂₃H₂₄FNO
• Molecular Weight: 349.448

Synonyms:2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide

Chemical Property of 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide

Chemical Property:

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Technology Process of 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide

There total 1 articles about 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

methylamine (74-89-5) + 2-(1-benzylidene-5-fluoro-2-methyl-1H-inden-3-yl)acetic acid → 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide (1346513-21-0) + 2-(5-fluoro-1-(4-isopropylbenzylidene)-2-methyl-1H-inden-3-yl)-N-methylacetamide (1346513-22-1)

Guidance literature:

2-(1-benzylidene-5-fluoro-2-methyl-1H-inden-3-yl)acetic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

methylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.ejmech.2013.01.012

upstream raw materials:

methylamine

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