Technology Process of <1-Methyl-3-(1,2,3,4-tetrahydro-4-methyl-3-phenyl-1-(phenylseleno)cyclopentindol-2-yl)-1H-indol-2-yl>phenylmethanone
There total 10 articles about <1-Methyl-3-(1,2,3,4-tetrahydro-4-methyl-3-phenyl-1-(phenylseleno)cyclopentindol-2-yl)-1H-indol-2-yl>phenylmethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
zinc(II) iodide;
In
dichloromethane;
for 1h;
Ambient temperature;
DOI:10.1021/jo00299a031
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 50 percent
2: 56 percent / SeO2 / dioxane / 48 h / Heating
3: 96 percent / tetrahydrofuran / -78 to 25 deg C
4: 83 percent / p-TsOH, molecular sieves / benzene / 0.08 h / Ambient temperature
5: ZnI2
With
selenium(IV) oxide; molecular sieve; toluene-4-sulfonic acid; zinc(II) iodide;
In
tetrahydrofuran; 1,4-dioxane; benzene;
DOI:10.1016/S0040-4020(01)80896-6
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 20 percent / HCl / ethanol / Δ
2: 90 percent / NaH / tetrahydrofuran
3: 56 percent / SeO2 / dioxane / 48 h / Heating
4: 96 percent / tetrahydrofuran / -78 to 25 deg C
5: 83 percent / p-TsOH, molecular sieves / benzene / 0.08 h / Ambient temperature
6: ZnI2
With
selenium(IV) oxide; molecular sieve; sodium hydride; toluene-4-sulfonic acid; zinc(II) iodide;
hydrogenchloride;
In
tetrahydrofuran; 1,4-dioxane; ethanol; benzene;
DOI:10.1016/S0040-4020(01)80896-6
