2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI)

Base Information

Chemical Name:2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI)
CAS No.:110658-87-2
Molecular Formula:C₈H₈F₃NO₂
Molecular Weight:207.152
Hs Code.:
Mol file:110658-87-2.mol

Synonyms:2-Oxa-3-azabicyclo[2.2.2]oct-5-ene,3-(trifluoroacetyl)- (9CI)

Suppliers and Price of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI)

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI)

There total 3 articles about 2-Oxa-3-azabicyclo[2.2.2]oct-5-ene, 3-(trifluoroacetyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 354-32-5
trifluoracetyl chloride

: 56239-25-9
2-Oxa-3-azabicyclo<2.2.2>oct-5-ene hydrochloride

: 110658-87-2
N-(trifluoroacetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-ene

Guidance literature:: With triethylamine; In dichloromethane; for 12h;
DOI:10.1021/ja00257a037

Reference yield:

: 121156-84-1
(1R,4S)-(+)-2-Oxa-3-azabicyclo<2.2.2>oct-5-en

: 407-25-0
trifluoroacetic anhydride

: 110568-59-7,110658-87-2
(1R,4S)-(-)-3-(Trifluoracetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-en

Guidance literature:: With dmap; In pyridine; dichloromethane; for 20h; Yield given; Ambient temperature;

Reference yield:

: 1165952-91-9
cyclohexa-1,3-diene

: 110658-87-2
N-(trifluoroacetyl)-2-oxa-3-azabicyclo<2.2.2>oct-5-ene

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / diethyl ether; ethanol / 48 h / 5 °C

2: 95 percent / triethylamine / CH₂Cl₂ / 12 h

With triethylamine; In diethyl ether; ethanol; dichloromethane;
DOI:10.1021/ja00257a037