3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether

Base Information

• Chemical Name: 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether
• CAS No.: 890661-94-6
• Molecular Formula: C₃₉H₃₄O₉
• Molecular Weight: 646.694
• Mol file: 890661-94-6.mol

Synonyms:3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether

Chemical Property of 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether

There total 4 articles about 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

3-bromotricetin 7-benzyl-3',4',5'-trimethylether (890661-91-3) + 2-Benzyloxy-4-bromo-1-methoxybenzene (78504-28-6) → 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether (890661-94-6)

Guidance literature:

2-Benzyloxy-4-bromo-1-methoxybenzene;

3-bromotricetin 7-benzyl-3',4',5'-trimethylether; iron(III)-acetylacetonate; In tetrahydrofuran; at -30 - -20 ℃; for 3h;

DOI:10.1016/j.tet.2006.02.024

Reference yield:

3-bromo-5-hydroxy-7-methoxy-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one → 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether (890661-94-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 237 mg / KHCO₃ / dimethylformamide / 2 h / 120 °C

2.2: 12 percent / Fe(acac)3 / tetrahydrofuran / 3 h / -30 - -20 °C

With potassium hydrogencarbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2006.02.024

Reference yield:

3-bromotricetin 3',4',5'-trimethyl ether (890661-90-2) → 3-(3''-benzyloxy-4''-methoxyphenyl)tricetin 7-benzyl-3',4',5'-trimethyl ether (890661-94-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / dimethylformamide / 20 h / 20 °C

2.1: 237 mg / KHCO₃ / dimethylformamide / 2 h / 120 °C

3.2: 12 percent / Fe(acac)3 / tetrahydrofuran / 3 h / -30 - -20 °C

With potassium carbonate; potassium hydrogencarbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2006.02.024

upstream raw materials:

3-bromotricetin 7-benzyl-3',4',5'-trimethylether

2-Benzyloxy-4-bromo-1-methoxybenzene

3-bromotricetin 3',4',5'-trimethyl ether

5,7-dihydroxy-3',4',5'-trimethoxyflavone