ETHYL STILBENE-4-CARBOXYLATE

Base Information

• Chemical Name: ETHYL STILBENE-4-CARBOXYLATE
• CAS No.: 109463-48-1
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• Mol file: 109463-48-1.mol

Synonyms:Benzoicacid, 4-(2-phenylethenyl)-, ethyl ester, (E)-; (E)-4-(2-Phenylethenyl)benzoicacid ethyl ester

Chemical Property of ETHYL STILBENE-4-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 3.65E-06mmHg at 25°C
• Melting Point: 110 °C
• Refractive Index: 1.622
• Boiling Point: 386°C at 760 mmHg
• Flash Point: 169.8°C
• PSA: 26.30000
• Density: 1.111g/cm³
• LogP: 4.03370
• Solubility.: soluble in Toluene

Purity/Quality:

98% ^*data from raw suppliers

Ethyl Stilbene-4-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl Stilbene-4-carboxylate is used in the synthesis of catalysts for Heck reactions.

Technology Process of ETHYL STILBENE-4-CARBOXYLATE

There total 33 articles about ETHYL STILBENE-4-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + Ethyl 4-bromobenzoate (5798-75-4) → (E)-ethyl 4-styrylbenzoate (1152-30-3,109463-49-2,109463-48-1)

Guidance literature:

With {4-[di(2-hydroxyethyl)amino]butyl}tri(n-butyl)ammonium bromide; palladium diacetate; at 100 ℃; for 6h; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2008.10.042

Reference yield: 98.0%

ethyl 4-vinylbenzoate (2715-43-7) + Diphenyliodonium triflate (66003-76-7) → (E)-ethyl 4-styrylbenzoate (1152-30-3,109463-49-2,109463-48-1)

Guidance literature:

With palladium diacetate; In N,N-dimethyl-formamide; at 130 ℃; for 0.0333333h; regioselective reaction; Schlenk technique; Microwave irradiation;

DOI:10.2174/1570178611310010011

Reference yield: 97.0%

ethyl 4-(2-phenylethynyl)benzoate (63164-96-5) → (E)-ethyl 4-styrylbenzoate (1152-30-3,109463-49-2,109463-48-1)

Guidance literature:

With ethanol; Ru(η(2)-2-(2'-pyridyl)phenyl)Cl(CO)(PPh3)2; sodium t-butanolate; at 110 ℃; for 1h; stereoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.organomet.0c00074

upstream raw materials:

ethyl 4-(diethoxyphosphorylmethyl)benzoate

benzaldehyde

p-carboethoxybenzenediazonium tetrafluoroborate

1-phenyl-1-(tributylstannyl)ethene

Downstream raw materials:

4-styrylbenzohydrazide

trans-4-stilbenemethanol

(2S,3R)-ethyl 3-phenyloxirane-2-carboxylate

p-ethoxycarbonylbenzaldehyde