(4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride

Base Information

• Chemical Name: (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride
• CAS No.: 810694-75-8
• Molecular Formula: C₁₄H₁₄Cl₂N₂O
• Molecular Weight: 297.184

Synonyms:(4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride

Chemical Property of (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride

Chemical Property:

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Technology Process of (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride

There total 1 articles about (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methyl-phenyl]-acetic acid (810694-73-6) → (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride (810694-75-8)

Guidance literature:

With oxalyl dichloride; In DMF (N,N-dimethyl-formamide); dichloromethane; Heating / reflux;

Reference yield: 62.0%

(4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride (810694-75-8) + 2-amino-2-cyclopropyl-propanenitrile (37024-73-0) → C20H23ClN4O (810694-01-0)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 7h;

Reference yield:

1-ethoxycarbonylhexahydropyridazine (5740-50-1) + (4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methylphenyl)acetic acid chloride (810694-75-8) → C21H27ClN4O3 (810694-55-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h;

upstream raw materials:

[4-(4-chloro-pyrazol-1-yl)-2-ethyl-6-methyl-phenyl]-acetic acid

Downstream raw materials:

C₂₁H₂₇ClN₄O₃

C₂₀H₂₃ClN₄O

C₁₉H₂₁ClN₄O₂

C₂₁H₂₆ClN₃O₃

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