C₈H₃BrClF₃O

Base Information

Chemical Name:C₈H₃BrClF₃O
CAS No.:1214349-47-9
Molecular Formula:C₈H₃BrClF₃O
Molecular Weight:287.463
Hs Code.:

C<sub>8</sub>H<sub>3</sub>BrClF<sub>3</sub>O

Synonyms:C₈H₃BrClF₃O

Suppliers and Price of C₈H₃BrClF₃O

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Chemical Property of C₈H₃BrClF₃O

Chemical Property:

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Technology Process of C₈H₃BrClF₃O

There total 3 articles about C₈H₃BrClF₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 654-97-7
5-bromo-2-(trifluoromethyl)benzoic acid

: 1214349-47-9
C₈H₃BrClF₃O

Guidance literature:: With thionyl chloride; at 85 ℃; for 2h;

Reference yield:

: 21740-00-1
5-bromo-2-iodo-benzoic acid

: 1214349-47-9
C₈H₃BrClF₃O

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / methanol / 16 h / Reflux

2: copper(I) bromide / 1-methyl-pyrrolidin-2-one / 5 h / 100 °C

3: lithium hydroxide; water / tetrahydrofuran / 3 h / 20 °C

4: thionyl chloride / dichloromethane / 0 - 80 °C

With thionyl chloride; sulfuric acid; water; copper(I) bromide; lithium hydroxide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane;

Reference yield:

: 181765-86-6
5-bromo-2-iodo-benzoic acid methyl ester

: 1214349-47-9
C₈H₃BrClF₃O

Guidance literature:: Multi-step reaction with 3 steps

1: copper(I) bromide / 1-methyl-pyrrolidin-2-one / 5 h / 100 °C

2: lithium hydroxide; water / tetrahydrofuran / 3 h / 20 °C

3: thionyl chloride / dichloromethane / 0 - 80 °C

With thionyl chloride; water; copper(I) bromide; lithium hydroxide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane;