tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate

Base Information

• Chemical Name: tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate
• CAS No.: 1160295-56-6
• Molecular Formula: C₂₁H₂₄ClN₃O₅S
• Molecular Weight: 465.958

Synonyms:tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate

Chemical Property of tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate

There total 1 articles about tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Indapamide (26807-65-8,77083-52-4) + di-tert-butyl dicarbonate (24424-99-5) → tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate (1160295-56-6)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 1.5h;

Reference yield:

tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate (1160295-56-6) + methyl 4-(2-bromoethyl)benzoate (136333-97-6) → methyl 4-{2-[(tert-butoxycarbonyl)({2-chloro-5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)carbamoyl]phenyl}sulphonyl)amino]ethyl}-benzoate (1184924-52-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 60 ℃; for 120h;

Reference yield:

tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate (1160295-56-6) + 4-bromophenylacetic acid (13737-36-5) → (4-{[(tert-butoxycarbonyl)({2-chloro-5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)carbamoyl]phenyl}sulphonyl)amino]methyl}phenyl)acetic acid (1184924-50-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 65 ℃; for 3h;

upstream raw materials:

Indapamide

di-tert-butyl dicarbonate

Downstream raw materials:

methyl 4-{2-[(tert-butoxycarbonyl)({2-chloro-5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)carbamoyl]phenyl}sulphonyl)amino]ethyl}-benzoate

(4-{[(tert-butoxycarbonyl)({2-chloro-5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)carbamoyl]phenyl}sulphonyl)amino]methyl}phenyl)acetic acid

Methyl 3-({(tert-butoxycarbonyl)[(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]-amino}methyl)benzoate

Methyl 4-{[(tert-butoxycarbonyl)({2-chloro-5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)carbamoyl]phenyl}sulphonyl)amino]-methyl}benzoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1160295-56-6 tert-Butyl [(2-chloro-5-{[(2-methyl-2,3-dihydro-1H-indol-1-yl)amino]carbonyl}phenyl)sulphonyl]carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send