1-BROMO-2-CHLOROBUTANE

Base Information

• Chemical Name: 1-BROMO-2-CHLOROBUTANE
• CAS No.: 108200-18-6
• Molecular Formula: C4H8 Br Cl
• Molecular Weight: 171.465
• Hs Code.: 2903799090
• Mol file: 108200-18-6.mol

Synonyms:1-BROMO-2-CHLOROBUTANE;2-CHLORO-1-BROMOBUTANE;1-BROMO-2-CHLOROBUTANE TECH

Chemical Property of 1-BROMO-2-CHLOROBUTANE

Chemical Property:

• Vapor Pressure: 7.15mmHg at 25°C
• Refractive Index: 1.466
• Boiling Point: 142°C at 760 mmHg
• Flash Point: 51.3°C
• PSA: 0.00000
• Density: 1.434g/cm³
• LogP: 2.39870

Purity/Quality:

98%Min ^*data from raw suppliers

1-BROMO-2-CHLOROBUTANE TECH 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-2-CHLOROBUTANE

There total 4 articles about 1-BROMO-2-CHLOROBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-butylene (106-98-9,9003-28-5) → 1,2-dichlorobutane (616-21-7,130232-87-0,130232-88-1) + 2-bromo-1-chlorobutane (79504-01-1) + 1,2-dibromobutane (533-98-2,130232-89-2,130232-90-5) + 1-bromo-2-chlorobutane (108200-18-6)

Guidance literature:

With bromine chloride; In tetrachloromethane; dichloromethane; at 0 ℃; Product distribution; other reagent;

DOI:10.1246/bcsj.59.2547

Reference yield:

1-bromo-butane (109-65-9) → 4-chlorobutyl bromide (6940-78-9) + 1-bromo-3-chlorobutane (56481-42-6) + 1-bromo-2-chlorobutane (108200-18-6)

Guidance literature:

With perchloric acid; 1-chloro-cis-2,6-dimethylpiperidine; In dichloromethane; water; at 0 ℃; for 2h; Overall yield = 53 percent; Irradiation; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.202100030

Reference yield:

1-butylene (106-98-9,9003-28-5) → 2-bromo-1-chlorobutane (79504-01-1) + 1-bromo-2-chlorobutane (108200-18-6)

Guidance literature:

With tetrabutylammonium dichlorobromate; In dichloromethane; at 0 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1246/bcsj.59.2547

upstream raw materials:

1-butylene

1-bromo-butane

Refernces

• 1、 Negoro, Takeshi,Ikeda, Yoshitsugu. "Bromochlorination of Alkenes with Dichlorobromate (1-) ion. IV. Regiochemistry of Bromochlorinations of Alkenes with Molecular Bromine Chloride and Dichlorobromate (1-) Ion". . p. 2547 - 2552. Retrieved 2007/10/02.