1-BROMO-3-CHLOROBUTANE

Base Information

• Chemical Name: 1-BROMO-3-CHLOROBUTANE
• CAS No.: 56481-42-6
• Molecular Formula: C4H8BrCl
• Molecular Weight: 171.465
• Mol file: 56481-42-6.mol

Synonyms:1-Bromo-3-chloro-2-propanone;2-Propanone,1-bromo-3-chloro;1-Brom-3-chlor-aceton;1-bromo-3-chloro-acetone;1-bromo-3-chloro-butane;1-bromo-3-chloro-propan-2-one;1-bromo-3-chloro-propanone;CTK4J8340;1-Brom-3-chlor-butan;bromo-3-chloro-propanone;AC1L3XJN;3-Chlor-1-brom-butan;

Chemical Property of 1-BROMO-3-CHLOROBUTANE

Chemical Property:

• PSA: 0.00000
• LogP: 2.39870

Purity/Quality:

99%, ^*data from raw suppliers

1-Bromo-3-chlorobutane 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-3-CHLOROBUTANE

There total 5 articles about 1-BROMO-3-CHLOROBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-chloro-1-methoxybutane (3565-66-0) → 1-bromo-3-chlorobutane (56481-42-6)

Guidance literature:

3-chloro-1-methoxybutane; With phosphorus tribromide; at 60 ℃;

With hydrogen bromide; at 100 ℃; for 1h; Further stages.;

DOI:10.1134/S0965544107020089

Reference yield:

1-bromo-butane (109-65-9) → 4-chlorobutyl bromide (6940-78-9) + 1-bromo-3-chlorobutane (56481-42-6) + 1-bromo-2-chlorobutane (108200-18-6)

Guidance literature:

With perchloric acid; 1-chloro-cis-2,6-dimethylpiperidine; In dichloromethane; water; at 0 ℃; for 2h; Overall yield = 53 percent; Irradiation; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.202100030

Reference yield:

1-bromo-4-butene (5162-44-7) → 1-bromo-3-chlorobutane (56481-42-6)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01155a069

upstream raw materials:

1-bromo-4-butene

3-chloro-1-methoxybutane

1,3-dibromobutane

1-bromo-butane

Downstream raw materials:

(2-{[7-(4-Chlorobutoxy)-6-methoxy-4-quinolyl]oxy}-5-methylphenyl)(phenyl)methanone