Cyclopropene, 1-bromo-3,3-dimethyl- (9CI)

Base Information

• Chemical Name: Cyclopropene, 1-bromo-3,3-dimethyl- (9CI)
• CAS No.: 108176-10-9
• Molecular Formula: C5H7 Br
• Molecular Weight: 147.015
• Hs Code.: 2903890090
• Mol file: 108176-10-9.mol

Synonyms:1-Bromo-3,3-dimethylcyclopropene

Chemical Property of Cyclopropene, 1-bromo-3,3-dimethyl- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 2.30500

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropene, 1-bromo-3,3-dimethyl- (9CI)

There total 3 articles about Cyclopropene, 1-bromo-3,3-dimethyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

1,1,3‐tribromo‐2,2‐dimethylcyclopropane (23534-97-6) → 1-bromo-3,3-dimethylcyclopropene (108176-10-9)

Guidance literature:

With methyllithium; In diethyl ether; at -78 ℃; for 0.166667h;

Reference yield:

1-chloro-2,2-dibromo-3,3-dimethylcyclopropane (23534-96-5) → 1-bromo-3,3-dimethylcyclopropene (108176-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) methyl-lithium, 2.) bromine / 1.) ether, -90 deg C; -75 deg C, 2 min, 2.) ether/carbon tetrachloride, -75 deg C

2: 31 percent / methyl-lithium / diethyl ether / 0.17 h / -78 °C

With methyllithium; bromine; In diethyl ether;

Reference yield:

chloro-trimethyl-silane (75-77-4) + 1-chloro-2,2-dibromo-3,3-dimethylcyclopropane (23534-96-5) → 3,3-dimethyl-1-(trimethylsilyl)-1-cyclopropene (107742-28-9) + 1-bromo-3,3-dimethylcyclopropene (108176-10-9)

Guidance literature:

With methyllithium; Multistep reaction. Title compound not separated from byproducts; 1.) ether, -40 - -30 deg C, 3 min, 2.) ether, -50 deg C, 5 min;

upstream raw materials:

chloro-trimethyl-silane

1-chloro-2,2-dibromo-3,3-dimethylcyclopropane

1,1,3‐tribromo‐2,2‐dimethylcyclopropane

Downstream raw materials:

2-methylbut-1-en-3-yne

3-bromo-3-methylbut-1-yne

Refernces