9H-Imidazo[1,2-a]purin-9-one, 5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI)

Base Information

• Chemical Name: 9H-Imidazo[1,2-a]purin-9-one, 5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI)
• CAS No.: 107698-73-7
• Molecular Formula: C₉H₉N₅O₄
• Molecular Weight: 251.202
• Mol file: 107698-73-7.mol

Synonyms:9H-Imidazo[1,2-a]purin-9-one,5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI)

Chemical Property of 9H-Imidazo[1,2-a]purin-9-one, 5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI)

Chemical Property:

• PSA: 124.34000
• LogP: -1.63960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9H-Imidazo[1,2-a]purin-9-one, 5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI)

There total 2 articles about 9H-Imidazo[1,2-a]purin-9-one, 5-acetyl-1,5,6,7-tetrahydro-6,7-dihydroxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide (19962-37-9) + Glyoxal (131543-46-9,107-22-2) → 5-acetyl-5,6,7,9-tetrahydro-9-oxo-(3H-imidazo<1,2-a>purine)-6,7-diol (107698-73-7)

Guidance literature:

With pyridine; Ambient temperature;

Reference yield:

2-amino-1,9-dihydro-6H-purin-6-one (73-40-5) → 5-acetyl-5,6,7,9-tetrahydro-9-oxo-(3H-imidazo<1,2-a>purine)-6,7-diol (107698-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / 1-methyl-2-pyrrolidone / 3 h / 145 °C

2: 74 percent / pyridine / Ambient temperature

With pyridine; 1-methyl-pyrrolidin-2-one;

Reference yield: 70.0%

acetic anhydride (108-24-7) + 5-acetyl-5,6,7,9-tetrahydro-9-oxo-(3H-imidazo<1,2-a>purine)-6,7-diol (107698-73-7) → 3,5-diacetyl-6,7-diacetoxy-5,6,7,9-tetrahydro-9-oxo(3H-imidazo<1,2-a>-purine) (105528-80-1)

Guidance literature:

With pyridine; for 2h; Ambient temperature;

upstream raw materials:

N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

Glyoxal

2-amino-1,9-dihydro-6H-purin-6-one

Downstream raw materials:

3,5-diacetyl-6,7-diacetoxy-5,6,7,9-tetrahydro-9-oxo(3H-imidazo<1,2-a>-purine)

6,7-diacetoxy-5-acetyl-5,6,7,9-tetrahydro-9-oxo-3H-iminazo[1,2-a]purine