(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

Base Information

Chemical Name:(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride
CAS No.:121269-57-6
Molecular Formula:C₁₉H₂₃NO₃*ClH
Molecular Weight:349.857
Hs Code.:

Synonyms:(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

Suppliers and Price of (R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

There total 1 articles about (R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-17-5
ethanol

: 121269-47-4
(3R,5R)-3-benzyl-4-tert-butyloxycarbonyl-5-phenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one

: 121269-57-6
(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1016/S0040-4039(00)82269-8

Reference yield: 61.0%

: 121269-57-6
(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

: 63060-94-6
D-phenylalanine ethyl ester hydrochloride

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 735.5 Torr;
DOI:10.1016/S0040-4039(00)82269-8

Reference yield:

: 121269-57-6
(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

: 121269-59-8
(R)-3-Phenyl-2-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionylamino)-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) H₂, PdCl₂, 2.) HCl/EtOH / 1.) EtOH, 15 psi, 24 h, 2.) reflux, 1 h

2: 77 percent / Et₃N / CHCl₃ / 0.5 h / Ambient temperature

With hydrogenchloride; ethanol; hydrogen; triethylamine; palladium dichloride; In chloroform;
DOI:10.1021/jo00277a032