(R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride

Base Information

Chemical Name:(R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride
CAS No.:63060-94-6
Molecular Formula:C11H15NO2.ClH
Molecular Weight:229.707
Hs Code.:2922499990
UNII:E55KWV5FN6

Synonyms:63060-94-6;D-PHENYLALANINE ETHYL ESTER HYDROCHLORIDE;(R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride;D-Phenylalanine, ethyl ester, hydrochloride;D-Phenylalanine ethyl ester, HCl;Ethyl D-phenylalaninate hydrochloride;(R)-Ethyl 2-amino-3-phenylpropionate HCl;(R)-Ethyl 2-amino-3-phenylpropionate hydrochloride;ethyl (2R)-2-amino-3-phenylpropanoate;hydrochloride;MFCD00198196;H-D-Phe-OEt HCl;H-D-Phe-OEt.HCl;ethyl (2R)-2-aminobutanoate,hydrochloride;E55KWV5FN6;SCHEMBL839857;FPFQPLFYTKMCHN-HNCPQSOCSA-N;AKOS025405195;AS-10699;D-?Phenylalanine ethyl ester hydrochloride;Phenylalanine ethyl ester hydrochloride, D-;CS-0151923;(R)-Ethyl2-amino-3-phenylpropanoatehydrochloride;A917584;D-Phenylalanine, ethyl ester, hydrochloride (1:1);ethyl (R)-2-amino-3-phenylpropionate hydrochloride

Suppliers and Price of (R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-Phenylalanine ethyl ester hydrochloride
5g
$ 369.00

TRC
D-PhenylalanineEthylEsterHydrochloride
100mg
$ 75.00

Crysdot
(R)-Ethyl2-amino-3-phenylpropanoatehydrochloride 95+%
100g
$ 456.00

Chem-Impex
D-Phenylalanine ethyl ester hydrochloride ≥ 99% (NMR)
100G
$ 709.00

Chem-Impex
D-Phenylalanineethylesterhydrochloride,99%(NMR) 99%(NMR)
25G
$ 213.92

Chem-Impex
D-Phenylalanine ethyl ester hydrochloride ≥ 99% (NMR)
1G
$ 15.50

Chem-Impex
D-Phenylalanineethylesterhydrochloride,99%(NMR) 99%(NMR)
5G
$ 52.19

Chemenu
(R)-Ethyl2-amino-3-phenylpropanoatehydrochloride 95%
100g
$ 426.00

American Custom Chemicals Corporation
D-PHENYLALANINE ETHYL ESTER HYDROCHLORIDE 95.00%
250MG
$ 727.65

American Custom Chemicals Corporation
D-PHENYLALANINE ETHYL ESTER HYDROCHLORIDE 95.00%
1G
$ 874.00

Total 31 raw suppliers

Chemical Property of (R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride

Chemical Property:

Melting Point:153-154 °C
PSA：52.32000
LogP:2.62180
Storage Temp.:Inert atmosphere,Room Temperature
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:229.0869564
Heavy Atom Count:15
Complexity:176

Purity/Quality:

99%, ^*data from raw suppliers

D-Phenylalanine ethyl ester hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=CC=C1)N.Cl
Isomeric SMILES:CCOC(=O)[C@@H](CC1=CC=CC=C1)N.Cl

Technology Process of (R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride

There total 6 articles about (R)-Ethyl 2-amino-3-phenylpropanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 64-17-5
ethanol

: 673-06-3,25191-15-5,658-69-5,67675-33-6
D-(R)-phenylalanine

: 63060-94-6
D-phenylalanine ethyl ester hydrochloride

Guidance literature:: With thionyl chloride; for 4h; Reflux;
DOI:10.1002/anie.202016589

Reference yield: 61.0%

: 121269-57-6
(R)-2-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-phenyl-propionic acid ethyl ester; hydrochloride

: 63060-94-6
D-phenylalanine ethyl ester hydrochloride

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 735.5 Torr;
DOI:10.1016/S0040-4039(00)82269-8

Reference yield:

: 100-39-0
benzyl bromide

: 63060-94-6
D-phenylalanine ethyl ester hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / sodium bis(trimethylsilyl)amide / tetrahydrofuran / 0.67 h / -78 °C

2: 93 percent / H₂ / PdCl₂ / tetrahydrofuran; ethanol / 20 h / 2585.7 Torr

3: 1 N HCl / 2 h / Heating

With hydrogenchloride; hydrogen; sodium hexamethyldisilazane; palladium dichloride; In tetrahydrofuran; ethanol;
DOI:10.1021/ja00024a038