tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate

Base Information

Chemical Name:tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate
CAS No.:107202-62-0
Molecular Formula:C15H27 N O3
Molecular Weight:269.384
Hs Code.:
DSSTox Substance ID:DTXSID20431251
Wikidata:Q82245094
Mol file:107202-62-0.mol

Synonyms:107202-62-0;ERYTHRO-N-BOC-L-CYCLOHEXYLALANINE EPOXIDE;tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate;Tert-butyl N-[(1S)-2-cyclohexyl-1-[(2S)-oxiran-2-yl]ethyl]carbamate;SCHEMBL7375658;[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane;DTXSID20431251;tert-Butyl((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate;AKOS015950208;PS-12901;(1S)-(1'-(S)-N-BOC-AMINO-2-CYCLOHEXYL-ETHYL)OXIRANE;tert-butyl (S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethylcarbamate;tert-Butyl (1S)-2-(cyclohexyl)-1-[(2S)-oxiran-2-yl]ethylcarbamate;tert-Butyl {(1S)-2-cyclohexyl-1-[(2S)-oxiran-2-yl]ethyl}carbamate

Suppliers and Price of tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chem-Impex
erythro-N-Boc-L-cyclohexylalanineepoxide,99%(HPLC) 99%(HPLC)
5G
$ 2856.00

Chem-Impex
erythro-N-Boc-L-cyclohexylalanineepoxide,99%(HPLC) 99%(HPLC)
1G
$ 627.20

Chem-Impex
erythro-N-Boc-L-cyclohexylalanineepoxide,≥99%(HPLC) ≥99%(HPLC)
100MG
$ 151.42

Chem-Impex
erythro-N-Boc-L-cyclohexylalanineepoxide,99%(HPLC) 99%(HPLC)
250MG
$ 280.00

Biosynth Carbosynth
[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane
500 mg
$ 400.00

Biosynth Carbosynth
[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane
250 mg
$ 250.00

Biosynth Carbosynth
[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane
100 mg
$ 205.00

Biosynth Carbosynth
[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane
50 mg
$ 128.00

Biosynth Carbosynth
[(1S)-(1'-(S)-N-Boc-amino-2-cyclohexylethyl)oxirane
25 mg
$ 63.00

American Custom Chemicals Corporation
ERYTHRO-N-BOC-L-CYCLOHEXYLALANINE EPOXIDE 95.00%
250MG
$ 612.15

Total 13 raw suppliers

Chemical Property of tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate

Chemical Property:

PSA：50.86000
LogP:3.63980
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:269.19909372
Heavy Atom Count:19
Complexity:305

Purity/Quality:

97% ^*data from raw suppliers

erythro-N-Boc-L-cyclohexylalanineepoxide,99%(HPLC) 99%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1CCCCC1)C2CO2
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H]2CO2

Technology Process of tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate

There total 8 articles about tert-Butyl ((S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 952685-46-0
tert-butyl (2S,3S)-4-chloro-1-cyclohexyl-3-hydroxybutan-2-ylcarbamate

: 107202-62-0
tert-butyl (S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethylcarbamate

Guidance literature:: With sodium hydroxide; In ethanol; for 1h;

Reference yield: 77.0%

: 104882-03-3
(2S,3S)-3-[(tert-butoxycarbonyl)amino]-4-cyclohexyl-1,2-butanediol

: 107202-62-0
tert-butyl (S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethylcarbamate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In chloroform; Heating;
DOI:10.1016/0040-4039(95)00415-9

Reference yield:

: 118388-73-1
(S)-2-tert-butyl 1-cyclohexyl-4-diazo-3-oxobutan-2-ylcarbamate

: 107202-62-0
tert-butyl (S)-2-cyclohexyl-1-((S)-oxiran-2-yl)ethylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: HCl / dioxane; diethyl ether / 1 h / 0 °C

2: NaBH₄ / tetrahydrofuran; H₂O / 0.75 h / 0 °C

3: KOH / ethanol / 1.5 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; In tetrahydrofuran; 1,4-dioxane; diethyl ether; ethanol; water;
DOI:10.1021/jm00038a005