Pyrrole-3-carboxylic acid, 2-methyl-5-nitro-, ethyl ester (6CI)

Base Information

• Chemical Name: Pyrrole-3-carboxylic acid, 2-methyl-5-nitro-, ethyl ester (6CI)
• CAS No.: 106840-79-3
• Molecular Formula: C₈H₁₀N₂O₄
• Molecular Weight: 198.178
• Mol file: 106840-79-3.mol

Synonyms:Pyrrole-3-carboxylicacid, 2-methyl-5-nitro-, ethyl ester (6CI)

Chemical Property of Pyrrole-3-carboxylic acid, 2-methyl-5-nitro-, ethyl ester (6CI)

Chemical Property:

• PSA: 87.91000
• LogP: 1.93120

Purity/Quality:

Ethyl2-Methyl-5-nitro-1H-pyrrole-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrrole-3-carboxylic acid, 2-methyl-5-nitro-, ethyl ester (6CI)

There total 4 articles about Pyrrole-3-carboxylic acid, 2-methyl-5-nitro-, ethyl ester (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-iodo-2-methyl-5-nitro-pyrrole-3-carboxylic acid ethyl ester (98491-26-0) → 2-Methyl-5-nitropyrrol-5-carbonsaeureethylester (106840-79-3)

Guidance literature:

With copper; acetic acid;

Reference yield:

2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester (936-12-9) → 2-Methyl-5-nitropyrrol-5-carbonsaeureethylester (106840-79-3)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous methanol; acetic acid; KI / Behandeln der erwaermten Loesung mit wss. H₂O₂

2: concentrated aqueous HNO₃

3: copper-powder; acetic acid

With methanol; nitric acid; copper; acetic acid; potassium iodide;

Reference yield:

ethyl 4,5-diiodo-2-methyl-1H-pyrrole-3-carboxylate (98491-31-7) → 2-Methyl-5-nitropyrrol-5-carbonsaeureethylester (106840-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated aqueous HNO₃

2: copper-powder; acetic acid

With nitric acid; copper; acetic acid;

upstream raw materials:

4-iodo-2-methyl-5-nitro-pyrrole-3-carboxylic acid ethyl ester

acetic acid

2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

ethyl 4,5-diiodo-2-methyl-1H-pyrrole-3-carboxylate