2-(2-Cyanoethylamino)-2-methylpropanoic acid

Base Information

Chemical Name:2-(2-Cyanoethylamino)-2-methylpropanoic acid
CAS No.:106556-63-2
Molecular Formula:C₇H₁₂N₂O₂
Molecular Weight:156.184
Hs Code.:2926909090
European Community (EC) Number:809-994-8
DSSTox Substance ID:DTXSID60544793
Mol file:106556-63-2.mol

Synonyms:2-(2-cyanoethylamino)-2-methylpropanoic acid;106556-63-2;2-((2-Cyanoethyl)amino)-2-methylpropanoic acid;MFCD12756521;N-(2-cyanoethyl)-2-methylalanine;Alanine, N-(2-cyanoethyl)-2-methyl- (9CI);2-[(2-CYANOETHYL)AMINO]-2-METHYLPROPANOIC ACID;2-(2-cyanoethylamino)-2-methylpropanoicacid;2-(2-Cyanoethylamino)-2-methyl-propanoic acid;SCHEMBL1190532;DTXSID60544793;JUSMPLVCKLEQRY-UHFFFAOYSA-N;AKOS014313993;NS-01214;SY018093;CS-0037362;EN300-747027;A895770

Suppliers and Price of 2-(2-Cyanoethylamino)-2-methylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-Cyanoethylamino)-2-methylpropanoicAcid
10mg
$ 45.00

SynQuest Laboratories
2-(2-Cyanoethylamino)-2-methylpropanoic acid
1 g
$ 280.00

Crysdot
2-(2-Cyanoethylamino)-2-methylpropanoicacid 97%
5g
$ 518.00

Apolloscientific
2-(2-Cyanoethylamino)-2-methylpropanoic acid 97%
1g
$ 237.00

AK Scientific
2-(2-Cyanoethylamino)-2-methylpropanoicacid
250mg
$ 221.60

AK Scientific
2-(2-Cyanoethylamino)-2-methylpropanoicacid
5g
$ 918.80

Activate Scientific
2-(2-Cyanoethylamino)-2-methylpropanoic Acid 95%
5 g
$ 818.00

Activate Scientific
2-(2-Cyanoethylamino)-2-methylpropanoic Acid 95%
1 g
$ 274.00

Total 22 raw suppliers

Chemical Property of 2-(2-Cyanoethylamino)-2-methylpropanoic acid

Chemical Property:

Melting Point:213℃
Refractive Index:1.473
PSA：73.12000
Density:1.108
LogP:0.74378
Storage Temp.:2-8°C
XLogP3:-2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:156.089877630
Heavy Atom Count:11
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

2-(2-Cyanoethylamino)-2-methylpropanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)O)NCCC#N

Technology Process of 2-(2-Cyanoethylamino)-2-methylpropanoic acid

There total 1 articles about 2-(2-Cyanoethylamino)-2-methylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 62-57-7
2-Aminoisobutyric acid

: 107-13-1,25014-41-9
acrylonitrile

: 106556-63-2
2--2-methylpropionic acid

Guidance literature:: With sodium hydroxide; In water; at 0 ℃; for 18h;

Reference yield:

: 106556-63-2
2--2-methylpropionic acid

: C₃₃H₃₅F₄N₆O⁽¹⁺⁾*Br^(1-)

Guidance literature:: Multi-step reaction with 7 steps

1.1: tetramethyl ammoniumhydroxide; triethylamine; dmap / acetonitrile / 10 h / 0 - 40 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 40 °C

3.1: sodium hydride / 1,4-dioxane / 3 h / 0 °C / Reflux

4.1: acetic acid; hydrazine / water; ethanol / 9 h / Reflux

5.1: N-ethyl-N,N-diisopropylamine / 2 h / -20 - 0 °C

5.2: 2 h / Reflux

6.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

7.1: N-ethyl-N,N-diisopropylamine / methanol / 3 h / 45 °C / pH 10

With dmap; tetramethyl ammoniumhydroxide; sodium hydride; potassium carbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; hydrazine; In 1,4-dioxane; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.ejmech.2021.113627

Reference yield:

: 106556-63-2
2--2-methylpropionic acid

: 1041015-44-4
5-(tert-butyl) 2-ethyl 3-benzamido-6,6-dimethylpyrrolo[3,4-c]pyrazole-2,5(4H,6H)-dicarboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: tetramethyl ammoniumhydroxide / water; acetonitrile / 53 h / 50 °C

2: potassium hydrogencarbonate / N,N-dimethyl-formamide / 20 - 40 °C

3: potassium tert-butylate / toluene / 0 - 5 °C

4: hydrazine hydrate; acetic acid / ethanol / 12 h / Reflux

5: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4.5 h / 0 - 20 °C

6: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 0 - 20 °C

With potassium tert-butylate; tetramethyl ammoniumhydroxide; potassium hydrogencarbonate; hydrazine hydrate; acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1021/jm300204j