(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

Base Information

Chemical Name:(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid
CAS No.:1394240-19-7
Molecular Formula:C₂₃H₂₁Cl₂NO₂S
Molecular Weight:446.397
Hs Code.:

Synonyms:(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

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Chemical Property of (2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

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Technology Process of (2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

There total 3 articles about (2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 52-90-4
L-Cysteine

: 5415-74-7
1,1-bis(4-chlorophenyl)-2-phenylethanol

: 1394240-19-7
(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

Guidance literature:: With boron trifluoride diethyl etherate; acetic acid; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.ejmech.2012.05.034

Reference yield:

: 90-98-2
4,4'-Dichlorobenzophenone

: 1394240-19-7
(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere

1.2: Saturated solution

2.1: boron trifluoride diethyl etherate; acetic acid / 2 h / 0 °C / Inert atmosphere

With boron trifluoride diethyl etherate; acetic acid; In tetrahydrofuran; 1.1: Grignard reaction;
DOI:10.1016/j.ejmech.2012.05.034

Reference yield:

: 6921-34-2
benzylmagnesium chloride

: 1394240-19-7
(2R)-2-amino-3-((1,1-bis(4-chlorophenyl)-2-phenylethyl)sulfanyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 24 h / 0 - 20 °C / Inert atmosphere

1.2: Saturated solution

2.1: boron trifluoride diethyl etherate; acetic acid / 2 h / 0 °C / Inert atmosphere

With boron trifluoride diethyl etherate; acetic acid; In tetrahydrofuran; 1.1: Grignard reaction;
DOI:10.1016/j.ejmech.2012.05.034