(4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone

Base Information

Chemical Name:(4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone
CAS No.:869304-72-3
Molecular Formula:C₁₈H₁₆N₂O₅
Molecular Weight:340.335
Hs Code.:
DSSTox Substance ID:DTXSID101168842

Synonyms:869304-72-3;DTXSID101168842;(4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone

Suppliers and Price of (4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:340.10592162
Heavy Atom Count:25
Complexity:504

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(N(C(=O)O1)C(=O)CC2=CC=C(C=C2)[N+](=O)[O-])CC3=CC=CC=C3
Isomeric SMILES:C1[C@H](N(C(=O)O1)C(=O)CC2=CC=C(C=C2)[N+](=O)[O-])CC3=CC=CC=C3

Technology Process of (4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone

There total 2 articles about (4R)-3-[2-(4-Nitrophenyl)acetyl]-4-(phenylmethyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 78507-53-6
4-nitrophenylacetyl fluoride

: 869304-72-3
4R-benzyl-3-(4-nitrophenylacetyl)-2-oxazolidinone

Guidance literature:: With n-butyllithium; triphenylmethane; In tetrahydrofuran; hexane; at -78 ℃; for 1h;
DOI:10.1002/jlcr.899

Reference yield:

: 104-03-0
4-nitrobenzeneacetic acid

: 869304-72-3
4R-benzyl-3-(4-nitrophenylacetyl)-2-oxazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / pyridine; cyanuric fluoride / acetonitrile / 3.5 h / 20 °C

2: 34 percent / triphenylmethane; n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

With pyridine; n-butyllithium; trifluoro-[1,3,5]triazine; triphenylmethane; In tetrahydrofuran; hexane; acetonitrile;
DOI:10.1002/jlcr.899