3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Base Information

Chemical Name:3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline
CAS No.:1295567-75-7
Molecular Formula:C₁₈H₁₁F₃IN₃O₃
Molecular Weight:501.203
Hs Code.:

Synonyms:3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

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Chemical Property of 3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Chemical Property:

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Technology Process of 3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

There total 3 articles about 3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62257-16-3
5-hydroxy-2-fluoroaniline

: 765962-75-2
3,5-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

: C₁₈H₁₁F₃IN₃O₃

: 1295567-75-7
3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 72h;

Reference yield:

: 29632-74-4
2-fluro-4-iodoaniline

: C₁₈H₁₁F₃IN₃O₃

: 1295567-75-7
3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 121 h / -10 - 0 °C

2: caesium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

With caesium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 315-14-0
1,3,5-trifluoro-2-nitrobenzene

: C₁₈H₁₁F₃IN₃O₃

: 1295567-75-7
3-(3-amino-4-fluorophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 121 h / -10 - 0 °C

2: caesium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

With caesium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide;