Technology Process of C22H24O2
There total 5 articles about C22H24O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); copper(l) iodide; triethylamine; triphenylphosphine;
In
toluene;
at 0 - 20 ℃;
for 24h;
Darkness;
Inert atmosphere;
DOI:10.1021/ol300718x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
1.2: 1 h / -78 - 20 °C / Inert atmosphere
2.1: potassium fluoride / dimethyl sulfoxide / 0.5 h / 20 °C / Inert atmosphere
3.1: copper(l) iodide; tris-(dibenzylideneacetone)dipalladium(0); triethylamine; triphenylphosphine / toluene / 24 h / 0 - 20 °C / Darkness; Inert atmosphere
With
potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); copper(l) iodide; magnesium; triethylamine; triphenylphosphine;
In
tetrahydrofuran; dimethyl sulfoxide; toluene;
3.1: Sonogashira coupling;
DOI:10.1021/ol300718x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
1.2: 1 h / -78 - 20 °C / Inert atmosphere
2.1: potassium fluoride / dimethyl sulfoxide / 0.5 h / 20 °C / Inert atmosphere
3.1: copper(l) iodide; tris-(dibenzylideneacetone)dipalladium(0); triethylamine; triphenylphosphine / toluene / 24 h / 0 - 20 °C / Darkness; Inert atmosphere
With
potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); copper(l) iodide; magnesium; triethylamine; triphenylphosphine;
In
tetrahydrofuran; dimethyl sulfoxide; toluene;
3.1: Sonogashira coupling;
DOI:10.1021/ol300718x
