methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate

Base Information

• Chemical Name: methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate
• CAS No.: 660838-99-3
• Molecular Formula: C₁₈H₁₉NO₃
• Molecular Weight: 297.354
• Mol file: 660838-99-3.mol

Synonyms:methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate

Chemical Property of methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate

There total 2 articles about methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride (7524-50-7) + 4-methoxy-benzaldehyde (123-11-5) → methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate (660838-99-3)

Guidance literature:

With sodium carbonate; In methanol; for 12h; Ambient temperature;

DOI:10.1055/s-1987-28189

Reference yield:

→ methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate (660838-99-3)

Guidance literature:

Reference yield:

methyl (E,S)-2-(4-methoxybenzylideneamino)-3-phenylpropionate (660838-99-3) → (S)-2-[(2R,3S)-3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester + (S)-2-[(2R,3R)-3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester + (S)-2-[(2S,3S)-3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester + (S)-2-[(2S,3R)-3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -40 ℃; for 23h;

DOI:10.1021/jo051890+

upstream raw materials:

methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

4-methoxy-benzaldehyde

Downstream raw materials:

(S)-2-[3-(4-Methoxy-phenyl)-oxaziridin-2-yl]-3-phenyl-propionic acid methyl ester

(S)-1-Methoxycarbonyl-2-phenylethylhydroxylamine