Technology Process of (2S)-N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alanine
There total 6 articles about (2S)-N,N'-bis-(phenylsulfonyl)-3-(2-pyrrolyl)alanine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical;
In
acetonitrile;
at 35 ℃;
sodium-phosphate buffer;
DOI:10.1016/j.tetlet.2010.11.089
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium carbonate / 1,4-dioxane; water
2: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / acetonitrile / 35 °C / sodium-phosphate buffer
With
sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium carbonate;
In
1,4-dioxane; water; acetonitrile;
DOI:10.1016/j.tetlet.2010.11.089
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 18-crown-6 ether; potassium tert-butylate / tetrahydrofuran / 0 °C
2: water; acetic acid / 50 °C
3: trifluoroacetic acid / dichloromethane
4: sodium carbonate / 1,4-dioxane; water
5: sodium chlorite; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / acetonitrile / 35 °C / sodium-phosphate buffer
With
sodium hypochlorite; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 18-crown-6 ether; potassium tert-butylate; water; sodium carbonate; acetic acid; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile;
DOI:10.1016/j.tetlet.2010.11.089
