1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate

Base Information

• Chemical Name: 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate
• CAS No.: 1101132-67-5
• Molecular Formula: C₂₁H₂₈N₂O₉S
• Molecular Weight: 484.527
• Mol file: 1101132-67-5.mol

Synonyms:1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate

Chemical Property of 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate

Chemical Property:

Purity/Quality:

>95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Tolpyralate is an imidazolinone based herbicide which may be used in crop prevention.

Technology Process of 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate

There total 9 articles about 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Chloroethyl methyl carbonate (80196-03-8) + 5-hydroxy-1-ethylpyrazol-4-yl 3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)phenyl ketone → 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate (1101132-67-5)

Guidance literature:

5-hydroxy-1-ethylpyrazol-4-yl 3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)phenyl ketone; With potassium carbonate; tetrabutylammomium bromide; In butanone; at 20 ℃; for 0.166667h;

1-Chloroethyl methyl carbonate; In butanone; at 20 ℃; Reflux;

Reference yield:

1-Chloroethyl methyl carbonate (80196-03-8) + (5-hydroxy-1-ethylpyrazol-4-yl)(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)phenyl)ketone potassium salt (1197388-39-8) → 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate (1101132-67-5)

Guidance literature:

With tetrabutylammomium bromide; In toluene; at 90 - 100 ℃; Product distribution / selectivity;

Reference yield:

3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoic acid → 1-(1-ethyl-4-(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl)-1H-pyrazol-5-yloxy)ethyl methyl carbonate (1101132-67-5)

Guidance literature:

Multi-step reaction with 4 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / chloroform / 3 h / 20 °C

2: triethylamine / toluene / 20 - 80 °C

3: potassium carbonate / N,N-dimethyl-formamide; toluene / 3 h / Reflux; Azeotropic dehydration

4: tetrabutylammomium bromide / toluene / 90 - 100 °C

With oxalyl dichloride; tetrabutylammomium bromide; potassium carbonate; triethylamine; N,N-dimethyl-formamide; In chloroform; N,N-dimethyl-formamide; toluene;

upstream raw materials:

1-Chloroethyl methyl carbonate

(5-hydroxy-1-ethylpyrazol-4-yl)(3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)phenyl)ketone potassium salt

3-(2-methoxyethoxy)-2-methyl-4-(methylsulfonyl)benzoyl chloride

2,6-dichlorotoluene

Refernces

• 1、 -. "HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS". Page/Page column 21. . Retrieved 2010/07/02.
• 2、 -. "PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM". Page/Page column 24. . Retrieved 2009/12/27.