80196-03-8Relevant articles and documents
Ketorolac derivative, pharmaceutical composition and preparation method and application thereof
-
Paragraph 0211-0214, (2022/01/08)
The present invention provides a ketorolac derivative shown in formula (I), a pharmaceutical composition and a method and application thereof. As a drug, the ketorolac derivative has better half-life, stability, good pharmacokinetic properties, high stabi
Benzodiazepine compound as well as preparation method and medical action thereof (by machine translation)
-
Paragraph 0229-0231, (2021/01/11)
The invention provides a benzodiazepine compound as well as a preparation method and a medicine effect thereof, and belongs to the field of chemical medicine. The benzodiazepine compound is a compound shown in formula I. Or a salt thereof, or a stereoisomer thereof, or a solvate thereof, or a eutectic thereof, or a composition thereof. The anesthetic effect of the compound of the invention is good, and the anesthetic effect of the compound is equivalent to that of Ramozolam, and even better than that of repirzolam, and particularly shows that the effective dosage is obviously reduced, and the duration and the recovery time are remarkably reduced. At the same time, in the rat tail vein anesthesia model, the compound of the present invention is remarkably improved in comparison with the quality of the Ramozolam wake-up. The compound has the advantages of high effectiveness, short duration, fast resuscitation and good tolerance, can be used for anesthesia induction, anesthesia maintenance and inter-day operation anesthesia, and has a good application prospect. (by machine translation)
NEW HYDROXYESTER DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
-
Page/Page column 26; 44, (2017/01/09)
Compounds of formula (1) wherein R1, R2, R3, R4, R5, R6, R7, R13, Ra, Rb, A and n are as defined in the description. Medicaments containing them