2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione

Base Information

• Chemical Name: 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione
• CAS No.: 1329428-66-1
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 1329428-66-1.mol

Synonyms:2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione

Chemical Property of 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione

There total 16 articles about 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C23H42O5Si → 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione (1329428-66-1)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; at 0 ℃; for 0.0166667h; chemoselective reaction;

DOI:10.1016/j.tetlet.2011.12.115

Reference yield: 62.0%

(3S,6R)-6-(2,5-dimethoxy-4-methylphenyl)-2-methylheptane-2,3-diol (1329428-64-9) → 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione (1329428-66-1)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tet.2011.03.064

Reference yield:

C15H22O4 (1360593-97-0) → 2-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-5-methylcyclohexa-2,5-diene-1,4-dione (1329428-66-1) + C15H22O4 (1360594-09-7)

Guidance literature:

With 18-crown-6 ether; caesium carbonate; In dichloromethane; at -25 ℃; for 7h;

DOI:10.1016/j.tetlet.2011.12.115

upstream raw materials:

(R)-3-[(R)-3-(2,5-dimethoxy-4-methylphenyl)butanoyl]-4-phenyloxazolidin-2-one

(R)-3-(2,5-dimethoxy-4-methylphenyl)butanoic acid

(R)-1,4-dimethoxy-2-(5-methoxypent-4-en-2-yl)-5-methylbenzene

(R)-4-(2,5-dimethoxy-4-methylphenyl)pentanal