N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Base Information

Chemical Name:N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine
CAS No.:1357487-08-1
Molecular Formula:C₄₇H₄₃N₂O₁₂P
Molecular Weight:858.838
Hs Code.:

N<sub>3</sub>,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Synonyms:N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Suppliers and Price of N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

There total 5 articles about N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1357486-89-5
tribenzyl phosphonodiazoacetate

: 94189-81-8
3,3'-O,N-dibenzoylthymidine

: 1357487-08-1
N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Guidance literature:: With dirhodium tetraacetate; In benzene; at 85 ℃; for 48h; Molecular sieve;
DOI:10.1016/j.tet.2011.12.077

Reference yield:

: 53243-58-6
α-dibenzylphosphonoacetic acid

: 1357487-08-1
N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: potassium tert-butylate / toluene / 0.42 h / 0 °C

2.2: 0 - 20 °C

3.1: dirhodium tetraacetate / benzene / 48 h / 85 °C / Molecular sieve

With dirhodium tetraacetate; potassium tert-butylate; potassium carbonate; In N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1016/j.tet.2011.12.077

Reference yield:

: 214919-21-8
(dibenzyloxyphosphoryl)acetic acid benzyl ester

: 1357487-08-1
N₃,3'-O-dibenzoyl-5'-O-[dibenzyl(benzyloxycarbonyl)phosphonomethyl]thymidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / toluene / 0.42 h / 0 °C

1.2: 0 - 20 °C

2.1: dirhodium tetraacetate / benzene / 48 h / 85 °C / Molecular sieve

With dirhodium tetraacetate; potassium tert-butylate; In toluene; benzene;
DOI:10.1016/j.tet.2011.12.077