3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one

Base Information

• Chemical Name: 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one
• CAS No.: 55293-94-2
• Molecular Formula: C₂₀H₂₂O₅
• Molecular Weight: 342.392
• Mol file: 55293-94-2.mol

Synonyms:3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one

Chemical Property of 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one

There total 4 articles about 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-bis-(3,4-dimethoxy-phenyl)-2-methyl-propionic acid (858492-48-5) → 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one (55293-94-2)

Guidance literature:

With sulfuric acid; acetic acid;

Reference yield:

3-(3,4-dimethoxyphenyl)-5,6-dimethoxy-2-methyl-1H-inden-1-one (102159-36-4) → 3c-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one (55293-94-2)

Guidance literature:

With palladium on activated charcoal; ethyl acetate; Hydrogenation;

DOI:10.1021/ja01110a028

Reference yield:

bis(3,4-dimethoxyphenyl)methanone (4131-03-7) → 3t-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-2r-methyl-indan-1-one (55293-94-2)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc / Hydrierung an Palladium/Kohle in Essigsaeure und anschliessend Hydrolyse mit wss. NaOH

2: polyphosphoric acid

With PPA; zinc;

DOI:10.1021/ja01110a028

upstream raw materials:

3-(3,4-dimethoxyphenyl)-5,6-dimethoxy-2-methyl-1H-inden-1-one

3,3-bis-(3,4-dimethoxy-phenyl)-2-methyl-propionic acid

1,2-dimethoxybenzene

bis(3,4-dimethoxyphenyl)methanone