2-acetamidoterephthalic acid

Base Information

• Chemical Name: 2-acetamidoterephthalic acid
• CAS No.: 99185-32-7
• Molecular Formula: C₁₀H₉NO₅
• Molecular Weight: 223.185
• Mol file: 99185-32-7.mol

Synonyms:2-acetamidoterephthalic acid

Chemical Property of 2-acetamidoterephthalic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetamidoterephthalic acid

There total 7 articles about 2-acetamidoterephthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-aminoterephthalic acid (10312-55-7) + acetyl chloride (75-36-5) → 2-acetamidoterephthalic acid (99185-32-7)

Guidance literature:

In tetrahydrofuran; at 80 ℃; for 12h;

DOI:10.1039/d1cc02104d

Reference yield: 82.0%

3-aminoterephthalic acid (10312-55-7) + acetic anhydride (108-24-7) → 2-acetamidoterephthalic acid (99185-32-7)

Guidance literature:

at 80 ℃; for 4h; Reflux;

DOI:10.1039/c4dt00219a

Reference yield:

4Zn(2+)*3C10H7NO5(2-)*O(2-) → 3-aminoterephthalic acid (10312-55-7) + 2-acetamidoterephthalic acid (99185-32-7)

Guidance literature:

With hydrogen chloride; In dimethylsulfoxide-d6; water-d2; Sonication;

DOI:10.1039/c3cc48586b

upstream raw materials:

N-(2,5-dimethylphenyl)acetamide

acetylamino-terephthalic acid-1-methyl ester

3-aminoterephthalic acid

acetic anhydride

Downstream raw materials:

4-oxo-3,4-dihydroquinazoline-7-carboxylic acid

acetylamino-terephthalic acid-4-methyl ester

3-aminoterephthalic acid

dimethyl aminoterephthalate