2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Base Information

Chemical Name:2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one
CAS No.:1382978-67-7
Molecular Formula:C₂₁H₂₀N₂O₃S
Molecular Weight:380.467
Hs Code.:

Synonyms:2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Suppliers and Price of 2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

There total 9 articles about 2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 5162-44-7
1-bromo-4-butene

: 1382978-65-5
2H-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

: 1382978-67-7
2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Guidance literature:: With tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c2ob25103e

Reference yield:

: 19005-93-7
1H-indol-2-ylcarboxaldehyde

: 1382978-67-7
2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: diethyl ether / 20 °C / Molecular sieve; Inert atmosphere

2.1: sodium tetrahydroborate / methanol / 2 h / 0 - 20 °C / Inert atmosphere

3.1: dmap / tetrahydrofuran / 1.67 h / 0 - 20 °C / Inert atmosphere

4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; Methanesulfonyl azide / acetonitrile / 2 h / 0 - 20 °C / Inert atmosphere

5.1: potassium hydroxide / water; acetonitrile

6.1: dirhodium tetraacetate / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

7.1: ammonium cerium (IV) nitrate / water; acetonitrile / 0.5 h / 0 °C / Inert atmosphere

7.2: 0.5 h / 20 °C

8.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran; hexane / 0 - 20 °C / Inert atmosphere

With dmap; dirhodium tetraacetate; sodium tetrahydroborate; ammonium cerium (IV) nitrate; tetra-(n-butyl)ammonium iodide; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; Methanesulfonyl azide; potassium hydroxide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; water; acetonitrile;
DOI:10.1039/c2ob25103e

Reference yield:

: C₂₆H₃₆N₂O₄SSi₂

: 1382978-67-7
2-(1-butenyl)-1,2,3b,8-tetrahydro-3-oxo-8-phenylsulfonylpyrrolo[3',4':1,3]cycloprop[1,2-b]indol-3(3aH)-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; Methanesulfonyl azide / acetonitrile / 2 h / 0 - 20 °C / Inert atmosphere

2.1: potassium hydroxide / water; acetonitrile

3.1: dirhodium tetraacetate / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

4.1: ammonium cerium (IV) nitrate / water; acetonitrile / 0.5 h / 0 °C / Inert atmosphere

4.2: 0.5 h / 20 °C

5.1: tetra-(n-butyl)ammonium iodide; sodium hydride / tetrahydrofuran; hexane / 0 - 20 °C / Inert atmosphere

With dirhodium tetraacetate; ammonium cerium (IV) nitrate; tetra-(n-butyl)ammonium iodide; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; Methanesulfonyl azide; potassium hydroxide; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
DOI:10.1039/c2ob25103e