(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

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Chemical Name:(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea
CAS No.:1417885-45-0
Molecular Formula:C₂₉H₂₅F₃N₆O₃S
Molecular Weight:594.617
Hs Code.:

Synonyms:(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

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Chemical Property of (Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

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Technology Process of (Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

There total 7 articles about (Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1417885-44-9
N-[[(2-isopropylphenyl)amino]thioxomethyl]N'-(2-methyl(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl))urea

: 96-32-2
bromoacetic acid methyl ester

: 1417885-45-0
(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

Guidance literature:: With sodium acetate; In ethanol; at 60 ℃;

Reference yield: 60.0%

: 1417885-44-9,1538588-05-4
C₂₇H₂₅F₃N₆O₂S

: 96-32-2
bromoacetic acid methyl ester

: 1417885-45-0
(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

Guidance literature:: With sodium acetate; In ethanol; at 60 ℃;

Reference yield:

: 1417885-97-2
methyl 2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)benzoate

: 1417885-45-0
(Z)-1-(3-(2-isopropylphenyl)-4-oxothiazolidin-2-ylidene)-3-(2-methyl-4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)urea

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydroxide / tetrahydrofuran; methanol

2.1: triethylamine; diphenyl phosphoryl azide / isopropyl alcohol / 20 °C / Inert atmosphere

3.1: 1,2-dichloro-ethane / 80 °C

3.2: 20 °C

4.1: sodium acetate / ethanol / 60 °C

With diphenyl phosphoryl azide; sodium acetate; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; 1,2-dichloro-ethane; isopropyl alcohol;