tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate

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Chemical Name:tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate
CAS No.:1155870-75-9
Molecular Formula:C₂₈H₃₅N₃O₅
Molecular Weight:493.603
Hs Code.:

Synonyms:tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate

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Chemical Property of tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate

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Technology Process of tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate

There total 1 articles about tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.6%

: 1155870-72-6
(2E)-3-(4-{[(1R)-6-tert-butoxy-1-methyl-6-oxohexyl]oxy}-6-phenylfuro[2,3-d]pyrimidin-5-yl)acrylic acid

: 75-04-7,85404-22-4
ethylamine

: 1155870-75-9
tert-Butyl (6R)-6-({5-[(1E)-3-(ethylamino)-3-oxoprop-1-en-1-yl]-6-phenylfuro[2,3-d]pyrimidin-4-yl}oxy)heptanoate

Guidance literature:: (2E)-3-(4-{[(1R)-6-tert-butoxy-1-methyl-6-oxohexyl]oxy}-6-phenylfuro[2,3-d]pyrimidin-5-yl)acrylic acid; With HATU; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

ethylamine; With N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide; at 20 ℃;