Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

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Chemical Name:Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester
CAS No.:340026-87-1
Molecular Formula:C₄₀H₅₁N₄O₉P
Molecular Weight:762.84
Hs Code.:

Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Synonyms:Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

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Chemical Property of Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

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Technology Process of Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

There total 1 articles about Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2622-07-3
hexaethylphosphorous triamide

: 15567-95-0
N-(2-hydroxyethyl)-N-methylethanamide

: 40615-39-2
5'-O-(4-4'-dimethoxytrityl)thymidine

: 340026-87-1
Diethyl-phosphoramidous acid 2-(acetyl-methyl-amino)-ethyl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester

Guidance literature:: hexaethylphosphorous triamide; 5'-O-(4-4'-dimethoxytrityl)thymidine; With diethylammonium tetrazolide; In acetonitrile; at 25 ℃; for 0.5h;

N-(2-hydroxyethyl)-N-methylethanamide; In acetonitrile; at 20 ℃; for 6h; Further stages.;
DOI:10.1021/ol0156852