2-Methyl-1h-indol-6-amine

Base Information

Chemical Name:2-Methyl-1h-indol-6-amine
CAS No.:102308-53-2
Molecular Formula:C9H10 N2
Molecular Weight:146.19
Hs Code.:
DSSTox Substance ID:DTXSID101312116
Mol file:102308-53-2.mol

Synonyms:2-methyl-1h-indol-6-amine;102308-53-2;1H-Indol-6-amine, 2-methyl-;1H-Indol-6-amine,2-methyl-(9CI);6-amino-2-methylindole;MFCD12924118;6-Amino-2-methyl-1H-indole;SCHEMBL394630;2-methyl-1H-indol-6-ylamine;OAIIKIWHCVTWKK-UHFFFAOYSA-N;DTXSID101312116;CEA30853;1H-INDOL-6-AMINE,2-METHYL-;AKOS006338528;CS-W006526;SB14901;AS-50943;SY007601;P11525

Suppliers and Price of 2-Methyl-1h-indol-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-1H-indol-6-amine
100mg
$ 375.00

Matrix Scientific
2-Methyl-1H-indol-6-amine 97.0%
1g
$ 826.00

Crysdot
2-Methyl-1H-indol-6-amine 95+%
1g
$ 490.00

Chemenu
2-Methyl-1H-indol-6-amine 95%
1g
$ 491.00

American Custom Chemicals Corporation
2-METHYL-1H-INDOL-6-AMINE 95.00%
5MG
$ 456.65

Alichem
2-Methyl-1H-indol-6-amine
1g
$ 519.75

Alichem
2-Methyl-1H-indol-6-amine
250mg
$ 224.70

AccelPharmtech
2-methyl-1H-Indol-6-amine 97.00%
300MG
$ 260.00

Total 11 raw suppliers

Chemical Property of 2-Methyl-1h-indol-6-amine

Chemical Property:

PSA：41.81000
LogP:2.63970
Storage Temp.:2-8°C(protect from light)
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:146.084398327
Heavy Atom Count:11
Complexity:147

Purity/Quality:

99%, ^*data from raw suppliers

2-Methyl-1H-indol-6-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(N1)C=C(C=C2)N
Uses 2-Methyl-1H-indol-6-amine is used in the synthesis of aza-podophyllotoxin derivatives, with some compounds exhibiting stronger growth inhibition activity in cancer cell lines (Zr-75-1, MCF7, KB, Gurav, DWD, Colo-205, A-549 and Hop62).

Technology Process of 2-Methyl-1h-indol-6-amine

There total 14 articles about 2-Methyl-1h-indol-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2,5-dinitrophenylacetone

: 102308-53-2
6-amino-2-methylindole

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In butan-1-ol; at 90 ℃; for 5h;

Reference yield: 8.0%

6-nitro-1H-indole-2-carboxylic acid ethyl ester (B-4-b): 6-nitro-1H-indole-2-carboxylic acid ethyl ester (B-4-b)

: 4993-93-5
4-nitro-1H-indole-2-carboxylic acid ethyl ester

: 102308-53-2
6-amino-2-methylindole

Guidance literature:: With NaOH; LiAlH₄; In tetrahydrofuran; water;

Reference yield:

: 134747-25-4
ethyl 2-[2-(3-nitrophenyl)hydrazinylidene]propanoate

: 102308-53-2
6-amino-2-methylindole

Guidance literature:: ethyl 2-[2-(3-nitrophenyl)hydrazinylidene]propanoate; In toluene; Reflux;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; Inert atmosphere; Reflux;

With sodium hydroxide; In water;