2-cyclopentylethynyl benzene

Base Information

• Chemical Name: 2-cyclopentylethynyl benzene
• CAS No.: 21777-87-7
• Molecular Formula: C₁₃H₁₄
• Molecular Weight: 170.254
• Mol file: 21777-87-7.mol

Synonyms:2-cyclopentylethynyl benzene

Chemical Property of 2-cyclopentylethynyl benzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-cyclopentylethynyl benzene

There total 18 articles about 2-cyclopentylethynyl benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclopentylacetylene (930-51-8) → 2-cyclopentylethynyl benzene (21777-87-7)

Guidance literature:

With copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; In triethylamine; at 25 ℃;

DOI:10.1016/j.tetlet.2007.11.040

Reference yield: 86.0%

phenylethynyl chloride (1483-82-5) + cyclopentylmagnesium chloride (32916-51-1) → 2-cyclopentylethynyl benzene (21777-87-7)

Guidance literature:

With iron(III)-acetylacetonate; 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride; In tetrahydrofuran; at 0 ℃; for 0.05h; Inert atmosphere;

DOI:10.1002/chem.201904480

Reference yield: 78.0%

1-cyclopentyl-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt + 1-methyl-4-((phenylethynyl)sulfonyl)benzene (28995-88-2) → 2-cyclopentylethynyl benzene (21777-87-7)

Guidance literature:

With Eosin Y; N-ethyl-N,N-diisopropylamine; In methanol; 1,2-dichloro-ethane; at 20 - 22 ℃; for 16h; chemoselective reaction; Irradiation; Inert atmosphere;

DOI:10.1021/acscatal.8b03437

upstream raw materials:

phenylacetylene

cyclopentene

Cyclopentane

phenylethynyl trifluoromethyl sulfone

Downstream raw materials:

2-cyclopentyl-3-phenyl-1H-indole-6-carboxylic acid methyl ester

3-cyclopentyl-2-phenyl-1H-indole-6-carboxylic acid methyl ester