Technology Process of benzyl (allyl 2,3-di-O-benzyl-β-D-galactopyranoside)uronate
There total 15 articles about benzyl (allyl 2,3-di-O-benzyl-β-D-galactopyranoside)uronate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl (allyl 2-O-benzyl-β-D-galactopyranosid)uronate;
With
di(n-butyl)tin oxide;
In
toluene;
for 2h;
Heating;
benzyl bromide;
With
tetrabutylammomium bromide;
In
toluene;
at 60 - 85 ℃;
for 4h;
DOI:10.1080/07328300008544125
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: (1S)-10-camphorsulfonic acid / acetonitrile / 2 h / 20 °C
2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.5 h / 0 °C
2.2: 2 h / 0 °C
3.1: acetic acid / water / 2 h / 80 °C
4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 1 h / 20 °C
5.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 16 h / Inert atmosphere
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; (1S)-10-camphorsulfonic acid; sodium hydride; potassium hydrogencarbonate; acetic acid;
In
dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; mineral oil;
DOI:10.1002/ejoc.201300180
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane; water / 1 h / 20 °C
2: potassium hydrogencarbonate / N,N-dimethyl-formamide / 16 h / Inert atmosphere
With
2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; potassium hydrogencarbonate;
In
dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201300180
