6-BENZYLOXY-HEXANAL

Base Information

• Chemical Name: 6-BENZYLOXY-HEXANAL
• CAS No.: 101492-91-5
• Molecular Formula: C13H18 O2
• Molecular Weight: 206.285
• Mol file: 101492-91-5.mol

Synonyms:6-Benzyloxyhexanal;NSC 686505

Chemical Property of 6-BENZYLOXY-HEXANAL

Chemical Property:

• PSA: 26.30000
• LogP: 2.96250

Purity/Quality:

6-Benzyloxyhexanal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-BENZYLOXY-HEXANAL

There total 19 articles about 6-BENZYLOXY-HEXANAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

6-Benzyloxy-1,1-dimethoxyhexane (148840-81-7) → 6-benzyloxy-1-hexanal (101492-91-5)

Guidance literature:

With toluene-4-sulfonic acid; In tetrahydrofuran; water; isopropyl alcohol; for 1h; Heating;

DOI:10.1055/s-1993-25874

Reference yield: 95.0%

6-benzyloxyhexan-1-ol (71126-73-3) → 6-benzyloxy-1-hexanal (101492-91-5)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In ethyl acetate; for 8h; Reflux;

DOI:10.1002/jlcr.3834

Reference yield: 74.0%

→ 6-benzyloxy-1-hexanal (101492-91-5)

Guidance literature:

With tetrafluoroboric acid diethyl ether complex; In chloroform; for 12h; Reflux;

With tetrabutyl ammonium fluoride; dihydrogen peroxide; potassium hydrogencarbonate; In methanol; at 20 ℃; for 2h;

upstream raw materials:

6-benzyloxy-hexanal-diethylacetal

6-Benzyloxy-1,1-dimethoxyhexane

6-benzyloxyhexan-1-ol

1,6-hexanediol

Downstream raw materials:

(3Z)-9-Benzyloxynon-3-enal

(3Z,6Z)-12-Benzyloxy-1,1-diisopropoxydodeca-3,6-diene

8-benzyloxy-3-hydroxy-octanoic acid methyl ester

Refernces

• 1、 Sakai, Yuki,Asakura, Yukiko,Morita, Mitsuhiro,Takahashi, Takashi. "Concise synthesis of hydroxy β -methyl fatty acid ethyl esters". . p. 1195 - 1198. Retrieved 2017.
• 2、 Mountanea, Olga G.,Limnios, Dimitris,Kokotou, Maroula G.,Bourboula, Asimina,Kokotos, George. "Asymmetric Synthesis of Saturated Hydroxy Fatty Acids and Fatty Acid Esters of Hydroxy Fatty Acids". . p. 2010 - 2019. Retrieved 2019.
• 3、 Van Der Heijden, Gydo,Kraakman, Jasper,Biemolt, Jasper,Ruijter, Eelco,Orru, Romano V. A.. "Metal-free one-pot α-carboxylation of primary alcohols". . p. 9716 - 9719. Retrieved 2016.