tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Base Information

Chemical Name:tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate
CAS No.:1374768-71-4
Molecular Formula:C₃₈H₄₈N₂O₉S
Molecular Weight:708.873
Hs Code.:

tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Synonyms:tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Suppliers and Price of tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

There total 14 articles about tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1374768-69-0
C₃₇H₄₄N₂O₉S

: 75-16-1
methylmagnesium bromide

: 1374768-70-3
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

: 1374768-71-4
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Guidance literature:: C₃₇H₄₄N₂O₉S; methylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 1h;

With ammonium chloride; In tetrahydrofuran; water;

Reference yield:

: 4704-18-1
(2S,3R,4R,5S,6R)-(6-(acetoxymethyl)-3-isothiocyanatotetrahydro-2H-pyran-2,4,5-triyl)triacetate

: 1374768-70-3
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

: 1374768-71-4
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Guidance literature:: Multi-step reaction with 8 steps

1.1: dichloromethane / 2 h / 0 °C

1.2: 12 h / 20 °C

1.3: Cooling with ice

2.1: potassium carbonate; methanol / 3 h / 20 °C

3.1: triethylamine / methanol / 5 h / 20 °C

4.1: triethylamine / dmap / dichloromethane / 12 h / 20 °C

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C

5.2: 1.5 h / 15 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C

7.1: N-Bromosuccinimide; potassium hydrogencarbonate / tetrabutylammomium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane; water / 0.5 h / 0 - 20 °C

8.1: tetrahydrofuran / 1 h / 20 °C

With methanol; N-Bromosuccinimide; tetrabutyl ammonium fluoride; sodium hydride; potassium carbonate; potassium hydrogencarbonate; triethylamine; dmap; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutylammomium bromide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 38336-04-8
O-benzylethanolamine

: 1374768-70-3
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

: 1374768-71-4
tert-butyl 2-(benzyloxy)ethyl((3aR,5R,6S,7R,7aR)-5-(1-hydroxyethyl)-6,7-bis(4-methoxybenzyloxy)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-2-yl)carbamate

Guidance literature:: Multi-step reaction with 8 steps

1.1: dichloromethane / 2 h / 0 °C

1.2: 12 h / 20 °C

1.3: Cooling with ice

2.1: potassium carbonate; methanol / 3 h / 20 °C

3.1: triethylamine / methanol / 5 h / 20 °C

4.1: triethylamine / dmap / dichloromethane / 12 h / 20 °C

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C

5.2: 1.5 h / 15 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C

7.1: N-Bromosuccinimide; potassium hydrogencarbonate / tetrabutylammomium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane; water / 0.5 h / 0 - 20 °C

8.1: tetrahydrofuran / 1 h / 20 °C

With methanol; N-Bromosuccinimide; tetrabutyl ammonium fluoride; sodium hydride; potassium carbonate; potassium hydrogencarbonate; triethylamine; dmap; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutylammomium bromide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;