Technology Process of dibutyl 5-nitroisophthalate
There total 1 articles about dibutyl 5-nitroisophthalate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
benzene;
Heating;
DOI:10.1021/ol050341n
- Guidance literature:
-
Multi-step reaction with 6 steps
1: hydrogen; 5%-palladium/activated carbon / 50 - 70 °C
2: sodium methylate / methanol / 55 - 60 °C
3: sulfuric acid; Iodine monochloride / water / 70 - 90 °C
4: N,N-dimethyl acetamide / 1 h / 90 - 95 °C
5: N,N-dimethyl acetamide / 18 h / 30 - 35 °C / Inert atmosphere; Large scale
6: sodium hydroxide; water / N,N-dimethyl acetamide / Large scale
With
sulfuric acid; 5%-palladium/activated carbon; water; hydrogen; sodium methylate; Iodine monochloride; sodium hydroxide;
In
methanol; N,N-dimethyl acetamide; water;
- Guidance literature:
-
With
ammonium formate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
for 1.5h;
Heating;
DOI:10.1021/ol050341n
